Difference between revisions of "CellularMemory:Hysteresis in Mammalian Cells"
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Kramer, B.P. and Fussenegger, M. 2005. [http://www2.davidson.edu/studentlife/stu_orgs/frisbee/Hysteresis%20in%20mammalian%20cells.pdf Hysteresis in a synthetic mammalian gene network.] ''Proc. Natl. Acad. Sci.'' '''102''': 9517-9522. | Kramer, B.P. and Fussenegger, M. 2005. [http://www2.davidson.edu/studentlife/stu_orgs/frisbee/Hysteresis%20in%20mammalian%20cells.pdf Hysteresis in a synthetic mammalian gene network.] ''Proc. Natl. Acad. Sci.'' '''102''': 9517-9522. | ||
| − | [[Image:Hysteresis.png|thumb|400px|left|'''A graphical depiction of hysteresis.''' Arrows indicate the direction of movement from one state to another. For a system that exists in | + | [[Image:Hysteresis.png|thumb|400px|left|'''A graphical depiction of hysteresis.''' Arrows indicate the direction of movement from one state to another. For a system that exists in the low output state initially (red line), a relatively high level of input is required to induce a change to a high system output. For a system that exists in the high state initially (blue line), a relatively low level of input is required to induce a change to a low system output. In other words, more extreme amounts of input are required to move out of a state than are required to move into a state (meaning that the system resists a change of state).]] |
Revision as of 22:11, 14 November 2007
Main Page | Biological Designs | Mathematical Models | Toggle Switch | Hysteresis | Permanent Memory | Conclusions | References
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Kramer, B.P. and Fussenegger, M. 2005. Hysteresis in a synthetic mammalian gene network. Proc. Natl. Acad. Sci. 102: 9517-9522.  A graphical depiction of hysteresis. Arrows indicate the direction of movement from one state to another. For a system that exists in the low output state initially (red line), a relatively high level of input is required to induce a change to a high system output. For a system that exists in the high state initially (blue line), a relatively low level of input is required to induce a change to a low system output. In other words, more extreme amounts of input are required to move out of a state than are required to move into a state (meaning that the system resists a change of state). |
