Difference between revisions of "Histone Deacetylase (Katie Richeson)"
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=Histone Deacetylase [http://img.jgi.doe.gov/cgi-bin/geba/main.cgi?section=GeneDetail&page=geneDetail&gene_oid=644029844 (644029844)] = | =Histone Deacetylase [http://img.jgi.doe.gov/cgi-bin/geba/main.cgi?section=GeneDetail&page=geneDetail&gene_oid=644029844 (644029844)] = | ||
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| + | == What is this gene? == | ||
| + | The Adopt a Genome Project claims that this gene's functionality is as a [http://img.jgi.doe.gov/cgi-bin/geba/main.cgi?section=GeneDetail&page=geneDetail&gene_oid=644029844 deacetylase, histone deacetylase/acetoin utilization protein] | ||
== What is a Histone Deacetylase? == | == What is a Histone Deacetylase? == | ||
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Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that influence transcription by removing or adding acetyl groups to lysine located near the amino termini of histone proteins. When HAT adds an acetyl group to a histone transcriptional activity changes, whereas deactylation leads to gene silencing. "HDACs are also involved in the reversible acetylation of non-histone proteins" [[http://www.vincibiochem.it/HistoneDeacetylase.htm Vinci-Biochem]]. | Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that influence transcription by removing or adding acetyl groups to lysine located near the amino termini of histone proteins. When HAT adds an acetyl group to a histone transcriptional activity changes, whereas deactylation leads to gene silencing. "HDACs are also involved in the reversible acetylation of non-histone proteins" [[http://www.vincibiochem.it/HistoneDeacetylase.htm Vinci-Biochem]]. | ||
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Histone Acetylation in eukarya is a form of epigenetic regulation, where the density of chromatin is affected leading to changes in transcriptional rates. | Histone Acetylation in eukarya is a form of epigenetic regulation, where the density of chromatin is affected leading to changes in transcriptional rates. | ||
[http://www.nature.com/nrd/journal/v1/n4/images/nrd772-f1.jpg[[Image:histonepicture.jpg]]] | [http://www.nature.com/nrd/journal/v1/n4/images/nrd772-f1.jpg[[Image:histonepicture.jpg]]] | ||
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| + | == Why | ||
Revision as of 23:36, 7 September 2009
Histone Deacetylase (644029844)
What is this gene?
The Adopt a Genome Project claims that this gene's functionality is as a deacetylase, histone deacetylase/acetoin utilization protein
What is a Histone Deacetylase?
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that influence transcription by removing or adding acetyl groups to lysine located near the amino termini of histone proteins. When HAT adds an acetyl group to a histone transcriptional activity changes, whereas deactylation leads to gene silencing. "HDACs are also involved in the reversible acetylation of non-histone proteins" [Vinci-Biochem].
Histone Acetylation in eukarya is a form of epigenetic regulation, where the density of chromatin is affected leading to changes in transcriptional rates.
== Why
