Difference between revisions of "Translational Bursting"
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==Translational Bursting is the Main Source of Stochasticity in Prokaryotes== | ==Translational Bursting is the Main Source of Stochasticity in Prokaryotes== | ||
| − | The amount of protein translated per strand of mRNA produced is a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. | + | The amount of protein translated per strand of mRNA produced is characterized as a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. As in the finite number effect, a wide range of transcriptional and translational machinery leads to a population of cells with a wide range of expressed proteins. |
=Factors that Influence Translational Bursting= | =Factors that Influence Translational Bursting= | ||
Revision as of 23:56, 12 November 2007
Translational Bursting is the Main Source of Stochasticity in Prokaryotes
The amount of protein translated per strand of mRNA produced is characterized as a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. As in the finite number effect, a wide range of transcriptional and translational machinery leads to a population of cells with a wide range of expressed proteins.
Factors that Influence Translational Bursting
Degredation, get there when you come to it.
Results
()1 figure for translational bursting
figure for how TB is better than FNE
