Difference between revisions of "Weekly Discussions"
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| − | = 19 January 2010 | + | = 19 January 2010 = |
Why make something noisy? | Why make something noisy? | ||
| − | + | * The benefit of sampling | |
| − | + | * or maybe trying every ombination along a spectrum | |
| − | + | * a maze | |
| − | + | * Minesweeper? - except a wrong turn can't be completely detrimental to the whole system .... maybe though - aging / death discussion | |
Positive feedback loops --> bistable, bimodal phenotype | Positive feedback loops --> bistable, bimodal phenotype | ||
| − | + | * ex. S. cerevisiae with galactose (Acar paper) - have 2 positive, 1 negative - negative allows switching between states | |
| − | + | * perhaps the two states can be complementary to each other | |
| − | + | * random on/off transition | |
| − | + | * barcodes? decoding, decrypting - combination lock-ish - bacteria as a random number generator - stops when it fits the "slot" | |
Meeting with Dr. Campbell | Meeting with Dr. Campbell | ||
| − | + | * went through papers | |
| − | + | * positive feedback loops are important | |
| − | + | * Minesweeper --> maybe Battleship | |
| − | + | * the aging papers Dr. C sent - thinking can somehow randomly switch something on, if beneficial to survival @ that time, will select for those and kill the others | |
| − | + | * maybe some cell differentiation using +/- feedback | |
| − | + | * maybe some antenna-ish like sampling - a Biosensor - cell has lots of sensors, randomly sample for something, if detect something with one of the sensors then report...do something else while other cells can keep sensing | |
Revision as of 19:02, 14 February 2010
19 January 2010
Why make something noisy?
- The benefit of sampling
- or maybe trying every ombination along a spectrum
- a maze
- Minesweeper? - except a wrong turn can't be completely detrimental to the whole system .... maybe though - aging / death discussion
Positive feedback loops --> bistable, bimodal phenotype
- ex. S. cerevisiae with galactose (Acar paper) - have 2 positive, 1 negative - negative allows switching between states
- perhaps the two states can be complementary to each other
- random on/off transition
- barcodes? decoding, decrypting - combination lock-ish - bacteria as a random number generator - stops when it fits the "slot"
Meeting with Dr. Campbell
- went through papers
- positive feedback loops are important
- Minesweeper --> maybe Battleship
- the aging papers Dr. C sent - thinking can somehow randomly switch something on, if beneficial to survival @ that time, will select for those and kill the others
- maybe some cell differentiation using +/- feedback
- maybe some antenna-ish like sampling - a Biosensor - cell has lots of sensors, randomly sample for something, if detect something with one of the sensors then report...do something else while other cells can keep sensing
