Difference between revisions of "Disease resistance to fungal diseases"
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[[Media:Potential_Genes_of_Interest.xlsx]] | [[Media:Potential_Genes_of_Interest.xlsx]] | ||
− | Background on Resistance (''R'') genes and avirulence (''Avr'') genes | + | '''Background on Resistance (''R'') genes and avirulence (''Avr'') genes''' ([http://www.annualreviews.org/doi/full/10.1146/annurev.arplant.48.1.575 Hammond-Kosack & Jones 1997) |
+ | |||
+ | -R genes are found in the plant, while corresponding Avr gene is in the pathogen | ||
+ | -presumed roles of R genes: | ||
+ | # help plants detect pathogenic Avr gene products | ||
+ | # initiate signal transduction pathways that will help defend against the pathogen | ||
+ | # "have the capacity to evolve new R gene specificities rapidly" | ||
+ | |||
+ | -if the R gene or corresponding pathogenic Avr gene are not present or altered, then plant is infected with the disease | ||
+ | |||
+ | The R protein recognizes the Avr gene product (ligand), activating a signal transduction cascade that initiates the defense against the pathogen. Thus, the R gene is turned on in healthy plants. R proteins must be able to evolve quickly in order to target new pathogens specifically. The evolution of the Avr genes directly impacts the evolution of the related R gene (coevolution). |
Revision as of 19:16, 12 February 2013
Media:Potential_Genes_of_Interest.xlsx
Background on Resistance (R) genes and avirulence (Avr) genes ([http://www.annualreviews.org/doi/full/10.1146/annurev.arplant.48.1.575 Hammond-Kosack & Jones 1997)
-R genes are found in the plant, while corresponding Avr gene is in the pathogen -presumed roles of R genes:
- help plants detect pathogenic Avr gene products
- initiate signal transduction pathways that will help defend against the pathogen
- "have the capacity to evolve new R gene specificities rapidly"
-if the R gene or corresponding pathogenic Avr gene are not present or altered, then plant is infected with the disease
The R protein recognizes the Avr gene product (ligand), activating a signal transduction cascade that initiates the defense against the pathogen. Thus, the R gene is turned on in healthy plants. R proteins must be able to evolve quickly in order to target new pathogens specifically. The evolution of the Avr genes directly impacts the evolution of the related R gene (coevolution).