Difference between revisions of "Davidson Missouri W"

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(Secondary Projects)
(The Team)
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{| border="1" cellpadding="5" cellspacing="0" align="center" width="75%"
 
|-
 
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! style="color: yellow; background-color: red;"| The Team
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! style="color: white; background-color: black;"| The Team
! style="color: yellow; background-color: red;" | The Faculty
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! style="color: white; background-color: black;" | The Faculty
! style="color: yellow; background-color: red;" | Team Logos
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! style="color: white; background-color: black;" | Team Logos
 
|-
 
|-
  
|style="color: red; background-color: black;" align="center"| '''Davidson'''
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|style="color: black; background-color: red;" align="center"| '''Davidson'''
[[Oyinade Adefuye|<span style="color:red">Oyinade Adefuye</span>]]
+
<b>
 +
[[Oyinade Adefuye|<span style="color:black">Oyinade Adefuye</span>]]
 
<br>
 
<br>
[[Will DeLoache|<span style="color:red">Will DeLoache</span>]]
+
[[Will DeLoache|<span style="color:black">Will DeLoache</span>]]
 
<br>
 
<br>
[[Jim Dickson|<span style="color:red">Jim Dickson</span>]]
+
[[Jim Dickson|<span style="color:black">Jim Dickson</span>]]
 
<br>
 
<br>
[[Andrew Martens|<span style="color:red">Andrew Martens</span>]]
+
[[Andrew Martens|<span style="color:black">Andrew Martens</span>]]
 
<br>
 
<br>
[[ Amber Shoecraft|<span style="color:red">Amber Shoecraft</span>]]
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[[ Amber Shoecraft|<span style="color:black">Amber Shoecraft</span>]]
 
<br>
 
<br>
[[Mike Waters|<span style="color:red">Mike Waters</span>]]
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[[Mike Waters|<span style="color:black">Mike Waters</span>]]
 +
</b>
  
|style="color: red; background-color: black;" align="center"|
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|style="color: red; background-color: red;" align="center"|
[[A. Malcolm Campbell|<span style="color:red">A. Malcom Campbell</span>]]
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<b>
 +
[[A. Malcolm Campbell|<span style="color:black">A. Malcom Campbell</span>]]
 
<br>
 
<br>
[[Karmella Haynes|<span style="color:red">Karmella Haynes</span>]]
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[[Karmella Haynes|<span style="color:black">Karmella Haynes</span>]]
 
<br>
 
<br>
[[Laurie Heyer|<span style="color:red">Laurie Heyer</span>]]
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[[Laurie Heyer|<span style="color:black">Laurie Heyer</span>]]
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</b>
  
 
|style="color: red; background-color: white;" align="center"|
 
|style="color: red; background-color: white;" align="center"|
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|-
 
|-
  
|style="color: yellow; background-color: black;" align="center"|'''Missouri Western'''
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|style="color: black; background-color: yellow;" align="center"|'''Missouri Western'''
[[Jordan Baumgardner|<span style="color:yellow;">Jordan Baumgardner</span>]]
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<b>
 +
[[Jordan Baumgardner|<span style="color:black;">Jordan Baumgardner</span>]]
 
<br>
 
<br>
[[Tom Crowley|<span style="color:yellow;">Tom Crowley</span>]]
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[[Tom Crowley|<span style="color:black;">Tom Crowley</span>]]
 
<br>
 
<br>
[[Lane H. Heard|<span style="color:yellow;">Lane H. Heard</span>]]
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[[Lane H. Heard|<span style="color:black;">Lane H. Heard</span>]]
 
<br>
 
<br>
[[Nickolaus Morton|<span style="color:yellow;">Nickolaus Morton</span>]]
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[[Nickolaus Morton|<span style="color:black;">Nickolaus Morton</span>]]
 
<br>
 
<br>
[[Michelle Ritter|<span style="color:yellow;">Michelle Ritter</span>]]
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[[Michelle Ritter|<span style="color:black;">Michelle Ritter</span>]]
 
<br>
 
<br>
[[Jessica Treece|<span style="color:yellow;">Jessica Treece</span>]]
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[[Jessica Treece|<span style="color:black;">Jessica Treece</span>]]
 
<br>
 
<br>
[[Matthew Unzicker|<span style="color:yellow;">Matthew Unzicker</span>]]
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[[Matthew Unzicker|<span style="color:black;">Matthew Unzicker</span>]]
 
<br>
 
<br>
[[Amanda Valencia|<span style="color:yellow;">Amanda Valencia</span>]]
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[[Amanda Valencia|<span style="color:black;">Amanda Valencia</span>]]
 +
</b>
  
|style="color: yellow; background-color: black;" align="center"|
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|style="color: yellow; background-color: yellow;" align="center"|
[[Todd Eckdahl|<span style="color:yellow;">Todd Eckdahl</span>]]
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<b>
 +
[[Todd Eckdahl|<span style="color:black;">Todd Eckdahl</span>]]
 
<br>
 
<br>
[[Jeff Poet|<span style="color:yellow;">Jeff Poet</span>]]
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[[Jeff Poet|<span style="color:black;">Jeff Poet</span>]]
 +
</b>
  
 
|style="color: red; background-color: white;" align="center"|[[Image:MWLogo.gif]]
 
|style="color: red; background-color: white;" align="center"|[[Image:MWLogo.gif]]
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<center>
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=The Problem=
 
=The Problem=
 
</center>
 
</center>

Revision as of 17:57, 6 July 2007

DMW-1.jpg

The Team

The Team The Faculty Team Logos
Davidson

Oyinade Adefuye
Will DeLoache
Jim Dickson
Andrew Martens
Amber Shoecraft
Mike Waters

A. Malcom Campbell
Karmella Haynes
Laurie Heyer

DavidsonLogo.gif

Missouri Western

Jordan Baumgardner
Tom Crowley
Lane H. Heard
Nickolaus Morton
Michelle Ritter
Jessica Treece
Matthew Unzicker
Amanda Valencia

Todd Eckdahl
Jeff Poet

MWLogo.gif



The Problem

In Depth Overview
Solving the HPP in vivo


Probability and Statistics


Gene Splitting


Controlling Expression


Hix Insertion


History


Hamiltonian Path Problem

As a part of iGEM2006, a combined team from Davidson College and Missouri Western State University reconstituted a hin/hix DNA recombination mechanism which exists in nature in Salmonella as standard biobricks for use in E. coli. The purpose of the 2006 combined team was to provide a proof of concept for a bacterial computer in using this mechanism to solve a variation of The Pancake Problem from Computer Science. This task utilized both biology and mathematics students and faculty from the two institutions.

For 2007, we continue our collaboration and our efforts to manipulate E. coli into mathematics problem solvers as we refine our efforts with the hin/hix mechanism to explore another mathematics problem, the Hamiltonian Path Problem. This problem was the subject of a groundbreaking paper by Adelman in 1994 (citation below) where a unique Hamiltonian path was found in vitro for a particular directed graph on seven nodes. We propose to make progress toward solving the particular problem in vivo.


AdelmanGraph.JPG


HamiltonianGraph.PNG



Secondary Projects

Project Short Description
Burnt Pancake Problem Flipping DNA "Pancakes" with hix "spatulas" until the pancakes are in the correct order and orientation
Traveling Salesperson Problem Solving the Hamiltonian Path Problem AND minimizing distance traveled
Gene Splitting Web Tool A Davidson iGEM 2007-designed primer sequencer for gene splitting
Backwards promotion and Read-Through Transcription Davidson's investigation into control of "leaky" gene expression




Team1.jpg
Team graph.jpg

Resources / Citations

Davidson's Wet Lab Protocols

Missouri Western's Wet Lab Protocols

Spliting Genes Web Tool

Compatibility of Plasmids

A Site with an FAQ on Wikis

  1. DMW Part Numbers for 2007 are BBa_I715000 to BBa_I715999.
  2. How to Name a New Part
  3. Entering the Part to the Registry
  4. How to Annotate a Part

Cool site for Breakfast [1]

Karen Acker's paper describing GFP and TetA(c) with Hix insertions [2]

Bruce Henschen's paper describing one-time flippable Hix sites [3]

Intro to Hamiltonian Path Problem and DNA [4]

Adleman, LM. Molecular Computation of Solutions To Combinatorial Problems. Science. 11 November 1994. Vol. 266. no. 5187, pp. 1021 - 1024

Sambrook and Russell. 2001. Molecular Cloning A Laboratory Manual. Cold Spring Harbor Laboratry Press. Cold Spring Harbor, New York pg. 1.145. 2007 June.