Difference between revisions of "January 14, 2016"

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(Created page with "''References'' *Secor, Stephen M., and Diamond, Jared. “Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping.” The Journal of Experimental Biology. 198 ...")
 
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== Article Discussions == 
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=== "Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping" (1995) === 
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*Small Intestine mass doubled and other organ masses also increased 1-3 days post-feeding. 
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*Post-feeding effects also includes upregulation of intestinal uptake transporters and hydrolytic enzymes. 
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*The mucosal layer of the small intestine experiences greater increase in mass as compared to the serosa.
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 +
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=== "A Vertebrate Model of Extreme Physiological Regulation" (1998) === 
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*Snake post-prandial responses are adaptive rather than phylogenetic.
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*We need to investigate the sglt-1 gene.
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 +
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=== Questions to Consider: === 
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*Transport Mechanism: 
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***Is there an increase in transcription? 
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***Is there a hormonal response? 
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***Are there post-translational modifications? 
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 +
*Can we find an ortholog and trace it back to the Burmese Python? 
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*Can we find intestinal genes involved in housekeeping, cell-proliferation, or up-take?
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*How will our results be affected if we only sampled serosa from the Small Intestine? 
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*How does the brush-border get bigger? 
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 +
 +
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 +
 +
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''References''   
 
''References''   
  
 
*Secor, Stephen M., and Diamond, Jared. “Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping.” The Journal of Experimental Biology. 198 (1995): 1313-1325.   
 
*Secor, Stephen M., and Diamond, Jared. “Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping.” The Journal of Experimental Biology. 198 (1995): 1313-1325.   
[http://www.bio.davidson.edu/Courses/Bio343/2016/1a_pay_B4_pumping_1995.pdf Secor and Diamond (1995)]
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:::::[http://www.bio.davidson.edu/Courses/Bio343/2016/1a_pay_B4_pumping_1995.pdf Secor and Diamond (1995)] 
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*Secor, Stephen M., and Diamond, Jared. “A vertebrate model of extreme physiological regulation.” Nature. 395 (1998): 659-662. 
 +
:::::{http://www.bio.davidson.edu/Courses/Bio343/2016/1b_physiology_feeding_1998.pdf Secor and Diamond (1998)]

Revision as of 18:52, 12 February 2016

Article Discussions

"Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping" (1995)

  • Small Intestine mass doubled and other organ masses also increased 1-3 days post-feeding.
  • Post-feeding effects also includes upregulation of intestinal uptake transporters and hydrolytic enzymes.
  • The mucosal layer of the small intestine experiences greater increase in mass as compared to the serosa.


"A Vertebrate Model of Extreme Physiological Regulation" (1998)

  • Snake post-prandial responses are adaptive rather than phylogenetic.
  • We need to investigate the sglt-1 gene.


Questions to Consider:

  • Transport Mechanism:
      • Is there an increase in transcription?
      • Is there a hormonal response?
      • Are there post-translational modifications?
  • Can we find an ortholog and trace it back to the Burmese Python?
  • Can we find intestinal genes involved in housekeeping, cell-proliferation, or up-take?
  • How will our results be affected if we only sampled serosa from the Small Intestine?
  • How does the brush-border get bigger?





References

  • Secor, Stephen M., and Diamond, Jared. “Adaptive Responses to Feeding in Burmese Pythons: Pay Before Pumping.” The Journal of Experimental Biology. 198 (1995): 1313-1325.
Secor and Diamond (1995)
  • Secor, Stephen M., and Diamond, Jared. “A vertebrate model of extreme physiological regulation.” Nature. 395 (1998): 659-662.
{http://www.bio.davidson.edu/Courses/Bio343/2016/1b_physiology_feeding_1998.pdf Secor and Diamond (1998)]