Difference between revisions of "Translational Bursting"
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[[Image:Protein_level_effects.png| 500 px]] figure for how TB is better than FNE | [[Image:Protein_level_effects.png| 500 px]] figure for how TB is better than FNE | ||
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<center>[[Promoter Kinetics |Next Section in Origins and Characterization]] | [[Origins and Characterization of Stochasticity | Back to Origins and Characterization Home]]</center> | <center>[[Promoter Kinetics |Next Section in Origins and Characterization]] | [[Origins and Characterization of Stochasticity | Back to Origins and Characterization Home]]</center> | ||
Revision as of 23:57, 12 November 2007
Translational Bursting is the Main Source of Stochasticity in Prokaryotes
The amount of protein translated per strand of mRNA produced is characterized as a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. As in the finite number effect, a wide range of transcriptional and translational machinery leads to a population of cells with a wide range of expressed proteins.
Factors that Influence Translational Bursting
Degredation, get there when you come to it.
Results
figure for how TB is better than FNE
