Synthetic Cellular Memory

Brief Introduction paragraph

Explanation of how things will be explained.

1. How to biologically construct memory?

2. Mathematical Models of these constructs

3. Examples of 3 different types of memory in 3 different types of organisms.

---A. In 2000, a genetic toggle switch was created in E. coli.

---B. In 2005, a hysteretic switch was created in mammalian cells.

---C. In 2007, a permanant cellular memory unit (meaning that it remembered being in a given state even when it no longer existed in that state) was created in yeast.

4. Conclusions and Future Directions of the Field