Difference between revisions of "Histone Deacetylase (Katie Richeson)"
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What is a Histone Deactylase? | What is a Histone Deactylase? | ||
| − | -- | + | Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that influence transcription by removing or adding acetyl groups to lysine located near the amino termini of histone proteins. When HAT adds an acetyl group to a histone transcriptional activity changes, whereas deactylation leads to gene silencing. "HDACs are also involved in the reversible acetylation of non-histone proteins" [[http://www.vincibiochem.it/HistoneDeacetylase.htm Vinci-Biochem]]. |
Revision as of 23:17, 7 September 2009
Histone Deactylase (644029844)
What is a Histone Deactylase?
Histone deacetylase (HDAC) and histone acetyltransferase (HAT) are enzymes that influence transcription by removing or adding acetyl groups to lysine located near the amino termini of histone proteins. When HAT adds an acetyl group to a histone transcriptional activity changes, whereas deactylation leads to gene silencing. "HDACs are also involved in the reversible acetylation of non-histone proteins" [Vinci-Biochem].
