Medical Applications of Synthetic Biology - Samantha Simpson
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Project Proposal
My project will be on mechanisms that allow E. Coli to sense differences in a biological environment and medical applications of these mechanisms.
Partial Bibliography
Anderson JC, et al. (2006) Environmentally controlled invasion of cancer cells by engineered bacteria. J. of Molecular Biology 355:619-27.
Critchley RJ, et al. (2004) Potential therapeutic applications of recombinant, invasive E. coli. Gene therapy 11:1224-33.
Garmory HS, et al. (2003) The use of live attenuated bacteria as a delivery system for heterologous antigens. J. of Drug Targeting 11:471-79.
Kobayashi H, et al. (2004) Programmable cells: Interfacing natural and engineered gene networks. PNAS 101:8414-19.