Difference between revisions of "Figure 6. Modularity of the AND gate."
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<b>Figure 6. Modularity of the AND gate.</b> | <b>Figure 6. Modularity of the AND gate.</b> | ||
| + | The modularity of the AND gate is demonstrated by reconnecting the gate to new inputs (natural promoters), and a new output (desired phenotype). | ||
| + | A. Exchanging the inputs: | ||
| + | *Input 1: The ''lux'' promoter, which responds to the quorum signal AI-1. | ||
| + | *Input 2: The ''mgrB'' promoter, which responds to the absence of exogenous magnesium via the PhoPQ two-component system. | ||
| + | |||
| + | B. Exchanging the output: | ||
| + | *Output: The ''inv'' gene, coding for invasin, a protein that allows bacteria to invade mammalian cells. | ||
(Image from Figure 6 of Anderson et al., 2007. Permission pending.) | (Image from Figure 6 of Anderson et al., 2007. Permission pending.) | ||
[[Image:AND_gate_fig_6.jpg]] | [[Image:AND_gate_fig_6.jpg]] | ||
Revision as of 05:30, 20 November 2007
Figure 6. Modularity of the AND gate.
The modularity of the AND gate is demonstrated by reconnecting the gate to new inputs (natural promoters), and a new output (desired phenotype).
A. Exchanging the inputs:
- Input 1: The lux promoter, which responds to the quorum signal AI-1.
- Input 2: The mgrB promoter, which responds to the absence of exogenous magnesium via the PhoPQ two-component system.
B. Exchanging the output:
- Output: The inv gene, coding for invasin, a protein that allows bacteria to invade mammalian cells.
(Image from Figure 6 of Anderson et al., 2007. Permission pending.)
