Figure 6. Modularity of the AND gate.
From GcatWiki
Figure 6. Modularity of the AND gate.
The modularity of the AND gate is demonstrated by reconnecting the gate to new inputs (natural promoters), and a new output (desired phenotype).
A. Exchanging the inputs:
- Input 1: The lux promoter, which responds to the quorum signal AI-1.
- Input 2: The mgrB promoter, which responds to the absence of exogenous magnesium via the PhoPQ two-component system.
B. Exchanging the output:
- Output: The inv gene, coding for invasin, a protein that allows bacteria to invade mammalian cells.
(Image from Figure 6 of Anderson et al., 2007. Permission pending.)
