Difference between revisions of "Helix-Slipping"
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| + | Helix-slipping uses a sequence that forms an imperfectly paired double-stranded stem that is flexible in its nucleotide base-pairing through a "slip-structure" mechanism. It does not allow for rational design and results in disruption or restoration of the hammerhead ribozyme in response to changes in the aptamer. | ||
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http://www.pnas.org/content/vol104/issue36/images/large/zpq0340773700003.jpeg | http://www.pnas.org/content/vol104/issue36/images/large/zpq0340773700003.jpeg | ||
Revision as of 12:09, 20 November 2007
Helix-slipping uses a sequence that forms an imperfectly paired double-stranded stem that is flexible in its nucleotide base-pairing through a "slip-structure" mechanism. It does not allow for rational design and results in disruption or restoration of the hammerhead ribozyme in response to changes in the aptamer.
http://www.pnas.org/content/vol104/issue36/images/large/zpq0340773700003.jpeg
Links
Applications of Ribozymes in Synthetic Systems - Danielle Jordan
