Difference between revisions of "WEEK THREE (January 30 - February 3)"
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| − | We have an X-prize type of challenge for you. | + | '''We have an X-prize type of challenge for you.''' |
| − | We are wondering if there are a set of [http://www.neb.com/nebecomm/EnzymeFinderSearchByTypeIIs.asp type IIs restriction enzymes] within which you could embed other type IIs restriction site(s) to do something useful or interesting. Perhaps you could improve upon Golden Gate assembly, or other methods in the paper reviewed by Becca [http://gcat.davidson.edu/mediawiki-1.15.0/images/c/ca/Synthetic_assembly_overview.pdf Tom Ellis Tom Adieac and Geoff S. Baldwin]. Or perhaps you can think of a way to represent a mathematical problem with combinations of sites. | + | We are wondering if there are a set of [http://www.neb.com/nebecomm/EnzymeFinderSearchByTypeIIs.asp type IIs restriction enzymes] ([http://rebase.neb.com/cgi-bin/asymmlist?9 also see RE Base]) within which you could embed other type IIs restriction site(s) to do something useful or interesting. Perhaps you could improve upon Golden Gate assembly, or other methods in the paper reviewed by Becca [http://gcat.davidson.edu/mediawiki-1.15.0/images/c/ca/Synthetic_assembly_overview.pdf Tom Ellis Tom Adieac and Geoff S. Baldwin]. Or perhaps you can think of a way to represent a mathematical problem with combinations of sites. |
You can work solo or in teams of your design. However, everyone must participate in this challenge. | You can work solo or in teams of your design. However, everyone must participate in this challenge. | ||
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Ethics paper for discussion in large group (all read): | Ethics paper for discussion in large group (all read): | ||
| − | '''Talking the Talk''' <br> | + | [http://www.nature.com/news/2010/100616/pdf/465867a.pdf '''Talking the Talk'''] <br> |
Colin Mcilswain <br> | Colin Mcilswain <br> | ||
Nature. Vol 465, page 867. | Nature. Vol 465, page 867. | ||
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Team 1 MONDAY = Alex, Nishita, Erich<br> | Team 1 MONDAY = Alex, Nishita, Erich<br> | ||
| − | '''Noise in Gene Expression: Origins, Consequences, and Control''' <br> | + | [http://www.sciencemag.org/content/309/5743/2010.full.pdf '''Noise in Gene Expression: Origins, Consequences, and Control'''] <br> |
Jonathan M. Raser and Erin K. O’Shea <br> | Jonathan M. Raser and Erin K. O’Shea <br> | ||
| − | Science. Vol. 309, page 2010 | + | Science. Vol. 309, page 2010<br> |
| + | |||
Team 2 TUESDAY = Ellen, Dancho, Kirsten<br> | Team 2 TUESDAY = Ellen, Dancho, Kirsten<br> | ||
| − | '''Synthetic Biology: Integrated Gene Circuits''' <br> | + | [http://www.sciencemag.org/content/333/6047/1244.full.pdf '''Synthetic Biology: Integrated Gene Circuits'''] <br> |
Nagarajan Nandagopal and Michael B. Elowitz<br> | Nagarajan Nandagopal and Michael B. Elowitz<br> | ||
| − | Science. Vol. 333, page 1244. | + | Science. Vol. 333, page 1244. <br> |
| + | |||
| − | Team 3 WEDNESDAY = Duke, Becca, Ben <br> | + | Team 3 WEDNESDAY '''2:30 pm''' = Duke, Becca, Ben <br> |
| − | '''Network Motifs: Simple Building | + | [http://www.sciencemag.org/content/298/5594/824.full.pdf '''Network Motifs: Simple Building Blocks of Complex Networks'''] <br> |
| − | Blocks of Complex Networks''' <br> | ||
R. Milo, S. Shen-Orr, et al<br> | R. Milo, S. Shen-Orr, et al<br> | ||
| − | Science. Vol. 298, page 824. | + | Science. Vol. 298, page 824.<br> |
| + | |||
| + | |||
| + | Everyone FRIDAY '''3:00 pm (one-time delayed start)''' | ||
Latest revision as of 03:16, 14 February 2012
We have an X-prize type of challenge for you.
We are wondering if there are a set of type IIs restriction enzymes (also see RE Base) within which you could embed other type IIs restriction site(s) to do something useful or interesting. Perhaps you could improve upon Golden Gate assembly, or other methods in the paper reviewed by Becca Tom Ellis Tom Adieac and Geoff S. Baldwin. Or perhaps you can think of a way to represent a mathematical problem with combinations of sites.
You can work solo or in teams of your design. However, everyone must participate in this challenge.
Ethics paper for discussion in large group (all read):
Talking the Talk
Colin Mcilswain
Nature. Vol 465, page 867.
Paper Presentations for Week Three:
Team 1 MONDAY = Alex, Nishita, Erich
Noise in Gene Expression: Origins, Consequences, and Control
Jonathan M. Raser and Erin K. O’Shea
Science. Vol. 309, page 2010
Team 2 TUESDAY = Ellen, Dancho, Kirsten
Synthetic Biology: Integrated Gene Circuits
Nagarajan Nandagopal and Michael B. Elowitz
Science. Vol. 333, page 1244.
Team 3 WEDNESDAY 2:30 pm = Duke, Becca, Ben
Network Motifs: Simple Building Blocks of Complex Networks
R. Milo, S. Shen-Orr, et al
Science. Vol. 298, page 824.
Everyone FRIDAY 3:00 pm (one-time delayed start)
