The Structure of Cyclooxygenase-1 after Aspirin has Transferred its Acetyl Group

See the structure of aspirin

See the structure of Cycloxygenase-1

See the amino acid structure of Cox-1

You can see the overall structure of cycloxygenase on a different page.

This chime tutorial focuses on the acetylation of cox-1 to block the binding of arachidonic acid, the substrate. The acetyl group is shown here in green.

Zoom out to see where this active site is within the entire enzyme