The Structure of Cyclooxygenase-1 after Aspirin has Transferred its Acetyl Group
See the structure of aspirin
See the structure of Cycloxygenase-1
See the amino acid structure of Cox-1
You can see the overall structure of cycloxygenase on a different page.
This chime tutorial focuses on the
acetylation of cox-1
to block the binding of arachidonic acid, the substrate. The acetyl group is shown here in green.
Zoom out to see where this active site is within the entire enzyme