ODCase Structure

3D Structure of ODCase

(Orotidine 5'-monophosphate decarboxylase)



3D Structure of ODCase



This is a homodimer of ODCase, bound with its substrate OMP. The structure was determined by X-ray crystallography. If you zoom in, you can see the four critical amino acids at the active site (lysine in blue and aspartic acid in red).

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Zoom in and look at the active site with substrate bound. The active site is shaded green with the electron clouds forming a solid surface in appearance.

Look at a cross-section of the binding site. Notice the CO2 that will be removed by this carboxylase is shown with its full electron cloud.

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