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Natural Drugs; Flavonoids and Stilbenes

Flavonoids are polyphenolic biochemical compounds that have been shown to have antioxidant effects. They are known to be found in fruits, vegetable, olive oil, cocoa and beverages such as tea and red wine.There are over 4000 known flavonoids subdivided based on chemical structure. [1] The most common flavonoids include anthocyanins, flavols, flavones, flavanones, flavan-3-ols, and isoflavones.

Flavonoids2.jpg <--- general Flavonoid structures ---> Flavonoids3.jpg [2]

One subgroup of flavonoids called anthocyanins, are found in the pigments of various foods and are most known for their health benefits. The anthocyanins may have benefits such as protection against DNA cleavage and enzyme inhibition, and increased cellular immune response and membrane strength. [3]

Stilbenes, like Flavonoids, are polyphenolic compounds have been the focus of clinical research for cancer prevention. [4] One of the most commonly known stilbene, resveratrol, has been shown to have anticancer properties and the ability to suppress proliferation of cancer cells.[5]

250px-Resveratrol.jpg <--- Resveratrol structure [6]