CellularMemory:Conclusions - Revision history

Wideloache: /* Real World Applications */

2007-12-06T20:00:35Z

‎Real World Applications

Wideloache: /* Testing our Assumptions of Biological Systems */

2007-12-06T19:50:20Z

‎Testing our Assumptions of Biological Systems

Wideloache at 19:38, 5 December 2007

2007-12-05T19:38:48Z

Wideloache: /* Real World Applications */

2007-11-29T19:02:07Z

‎Real World Applications

Wideloache at 17:39, 20 November 2007

2007-11-20T17:39:56Z

Wideloache: /* Conclusions */

2007-11-16T07:16:24Z

‎<center>Conclusions</center>

Wideloache at 22:44, 14 November 2007

2007-11-14T22:44:15Z

Wideloache at 22:26, 14 November 2007

2007-11-14T22:26:04Z

Wideloache at 22:18, 14 November 2007

2007-11-14T22:18:22Z

Wideloache at 21:19, 14 November 2007

2007-11-14T21:19:40Z

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 ==Real World Applications==
-In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation ([[CellularMemory:References |Gardner, 2000 and Ajo-Franklin, 2007]]).
+In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. To create modularity, the inputs and outputs of memory circuits need to be changeable. As our library of activators/repressors expands, it will be easier to construct memory circuits that are sensitive to a variety of environmental inputs. Memory outputs can be modified by exchanging a reporter gene with a gene or set of genes that will perform some specific cellular function.  Obvious real world applications of such memory circuits include the detection of harmful chemicals in various environments (e.g. drinking water) and computation through the use of living organisms. When included in more complex gene networks, modular cellular memory could be implemented in gene therapies and in the engineering of controlled cell differentiation ([[CellularMemory:References |Gardner, 2000 and Ajo-Franklin, 2007]]).
 <hr>

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 ==Testing our Assumptions of Biological Systems==
-One of the most important aspects of synthetic biology is that it allows us to definitively test our knowledge of systems biology. By building rationally designed networks of genes, we can determine if our understanding of how networks function is incomplete. At such an early stage in the development of the field of synthetic biology, the construction of synthetic cellular memory in particular is an effective method of performing these tests of our understanding. The memory networks described in this paper are relatively simple, and they closely mimic common networks that are observed in nature. Based on the accuracy of the mathematical models that were presented in the three papers discussed, it is obvious that we have a fairly accurate level of understanding of these simple networks. Establishing simple but functional networks will allow for more effective troubleshooting of more complex networks. In this way, synthetic biology can build on past research of simple systems to find holes in our understanding of complex systems.
+One of the most important aspects of synthetic biology is that it allows us to definitively test our knowledge of systems biology. By building rationally designed networks of genes, we can determine if our understanding of how networks function is incomplete. At such an early stage in the development of the field of synthetic biology, the construction of synthetic cellular memory is a particularly effective method of performing these tests of our understanding. The memory networks described in this paper are relatively simple, and they closely mimic common networks that are observed in nature. Based on the accuracy of the mathematical models that were presented in the three papers discussed, it is obvious that we have a fairly accurate level of understanding of these simple networks. Establishing simple but functional networks will allow for more effective troubleshooting of more complex networks. In this way, synthetic biology can build on past research of simple systems to find holes in our understanding of complex systems.
 ==Real World Applications==

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 ==Real World Applications==
-In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation ([[CellularMemory:References |Gardner, 2000 and Ajo-Franklin, 2007]])..
+In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation ([[CellularMemory:References |Gardner, 2000 and Ajo-Franklin, 2007]]).
 <hr>

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 ==Real World Applications==
-In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation.
+In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation ([[CellularMemory:References |Gardner, 2000 and Ajo-Franklin, 2007]])..
 <hr>

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 =<center>Conclusions</center>=
-Why is synthetic memory important:
+==Testing our Assumptions of Biological Systems==
-# allows us to test our assumptions about how networks work in living systems
+==Real World Applications==
-# possible real world applications
+In the long run, modular synthetic cellular memory circuits will likely be used in many different types of synthetic devices. Obvious applications include the detection of harmful chemicals in various environments and computation through the use of living organisms. When included in more complex gene networks, cellular memory could have uses in the development of gene therapies and in the engineering of controlled cell differentiation.
 <hr>

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 <hr>
 <center>
-[[CellularMemory:Permanant Memory in Eukaryotes | <Previous Section]] | [[CellularMemory:References | Next Section>]]
+[[CellularMemory:Permanent Memory in Eukaryotes | <Previous Section]] | [[CellularMemory:References | Next Section>]]
 </center>

← Older revision		Revision as of 22:26, 14 November 2007
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	# possible real world applications		# possible real world applications
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		+	<center>
		+	[[CellularMemory:Permanant Memory in Eukaryotes \| <Previous Section]] \| [[CellularMemory:References \| Next Section>]]
		+	</center>

← Older revision		Revision as of 22:18, 14 November 2007
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		+	=<center>Conclusions</center>=

	Why is synthetic memory important:		Why is synthetic memory important:

← Older revision		Revision as of 21:19, 14 November 2007
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		+	Why is synthetic memory important:
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		+	# allows us to test our assumptions about how networks work in living systems
		+	# possible real world applications