Davidson College Synthetic Biology Seminar (Fall 2007) - Revision history

Wideloache at 20:47, 5 December 2007

2007-12-05T20:47:05Z

Wideloache at 19:03, 29 November 2007

2007-11-29T19:03:14Z

Wideloache at 19:02, 29 November 2007

2007-11-29T19:02:56Z

Emgarren: /* Our Papers */

2007-11-27T21:24:17Z

‎Our Papers

Emgarren at 21:19, 27 November 2007

2007-11-27T21:19:49Z

Emgarren at 21:17, 27 November 2007

2007-11-27T21:17:57Z

Emgarren at 21:15, 27 November 2007

2007-11-27T21:15:38Z

Emgarren at 21:14, 27 November 2007

2007-11-27T21:14:23Z

Emgarren: /* Our Papers */

2007-11-27T21:06:57Z

‎Our Papers

Emgarren: /* Our Papers */

2007-11-27T21:06:28Z

‎Our Papers

← Older revision		Revision as of 20:47, 5 December 2007
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		+	__NOTOC__
	== Davidson College Synthetic Biology Seminar, Fall 2007 ==		== Davidson College Synthetic Biology Seminar, Fall 2007 ==
	Click [http://www.bio.davidson.edu/Courses/Synthetic/synthetic_Seminar.html here] to access the class webpage		Click [http://www.bio.davidson.edu/Courses/Synthetic/synthetic_Seminar.html here] to access the class webpage

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 [[CellularMemory:Main Page | Synthetic Cellular Memory - Will DeLoache]]
-Synthetic cellular memory refers to the engineering of living organisms to produce "a protracted response to a transient stimulus" ([http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Ajo-Franklin, 2007]). The construction of such rationally designed memory mechanisms in living organisms provides a more thorough understanding of naturally occurring gene networks. In the future, modular cellular memory networks will likely be a key component of many synthetic biological designs, ranging from biocomputing to engineered cell differentiation [http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Gardner, 2000]).
+Synthetic cellular memory refers to the engineering of living organisms to produce "a protracted response to a transient stimulus" ([http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Ajo-Franklin, 2007]). The construction of such rationally designed memory mechanisms in living organisms provides a more thorough understanding of naturally occurring gene networks. In the future, modular cellular memory networks will likely be a key component of many synthetic biological designs, ranging from biocomputing to engineered cell differentiation ([http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Gardner, 2000]).
 [[Medical Applications of Synthetic Biology - Samantha Simpson]]

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 [[CellularMemory:Main Page | Synthetic Cellular Memory - Will DeLoache]]
-Synthetic cellular memory refers to the engineering of living organisms to produce "a protracted response to a transient stimulus" ([http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Ajo-Franklin, 2007]). The construction of such rationally designed memory mechanisms in living organisms provides a more thorough understanding of naturally occurring gene networks. In the future, modular cellular memory networks will likely be a key component of many synthetic biological designs, ranging from biocomputing to engineered cell differentiation.
+Synthetic cellular memory refers to the engineering of living organisms to produce "a protracted response to a transient stimulus" ([http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Ajo-Franklin, 2007]). The construction of such rationally designed memory mechanisms in living organisms provides a more thorough understanding of naturally occurring gene networks. In the future, modular cellular memory networks will likely be a key component of many synthetic biological designs, ranging from biocomputing to engineered cell differentiation [http://gcat.davidson.edu/GcatWiki/index.php/CellularMemory:References Gardner, 2000]).
 [[Medical Applications of Synthetic Biology - Samantha Simpson]]

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 ===Our Papers===
-Students in the synthetic biology seminar each chose a topic in synthetic biology on which to write a paper. With our selections, we do not claim to cover all aspects of synthetic biology but instead to provide an overview on subjects we found interesting.  The topics we chose can be classified within three broader areas of synthetic biology research:
+Students in Dr. Campbell's Fall 2007 Synthetic Biology Seminar each wrote a paper on a specific topic within the field of synthetic biology. With our selections, we do not claim to cover all aspects of synthetic biology, but instead hope to provide an overview on subjects we found interesting.  The topics we chose can be classified under three broader areas of synthetic biology research:
 #<b>Designng and Optimizing Tools.</b>  Mike, Laura, Hunter

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 *<b>Nanotechnology.</b>
 *<b>Engineering the minimal cell.</b> Scientists are trying to identify or build a cell that contains only those elements necessary to be able to classify it as "living."  Bot top-down (Venter) and bottom-up (Luisi) approaches are being used.  This research could shed light on the earliest origins of life, as well as provide a vessel (chassis?  I don't know correct use of this word...) for engineering synthetic biological functions that avoids the variables typically encountered when introducing a synthetic pathway into a cell.
+*Other ideas?

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 Using restriction enzymes and recombinant DNA, scientists focused on areas as diverse as biofuels, cellular memory, and directed evolution. Synthetic biology now captures a wide range of disciplines that all hold one thing in common: engineering genomes using preexisting and new biological systems and components. Mathematical modeling informs the design of the synthetic system, device, or circuit, which is implemented in wet lab experiments. Results from experimentation enhance the model. The ultimate goal of synthetic biology, therefore, is not only building novel biological systems, but creating a better understanding of existing ones.
-Some interesting images?
+===Synthetic Biology in the Media===
 ===Our Papers===

← Older revision		Revision as of 21:14, 27 November 2007
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	Directed evolution is a method of cellular engineering that uses Darwinian selection to evolve proteins and RNA with desirable properties not found in nature. The reliance of this method on the randomness of mutation and nature's selective properties sharply contrasts to the logical modeling and reasoning associated with traditional synthetic methods. Some might say that the lack of planning involved with directed evolution means it is constitutionally different than synthetic biology. Regardless, the method has been shown to be effective in achieving desired results in a number of cases, and could prove instrumental in the optimization of synthetically-designed constructs.		Directed evolution is a method of cellular engineering that uses Darwinian selection to evolve proteins and RNA with desirable properties not found in nature. The reliance of this method on the randomness of mutation and nature's selective properties sharply contrasts to the logical modeling and reasoning associated with traditional synthetic methods. Some might say that the lack of planning involved with directed evolution means it is constitutionally different than synthetic biology. Regardless, the method has been shown to be effective in achieving desired results in a number of cases, and could prove instrumental in the optimization of synthetically-designed constructs.
		+
		+	===Other Interesting Areas of Research===
		+
		+	Here we could put a brief summary of some other areas of synthetic biology research that are not covered in by any of our papers. These might include:
		+
		+	*<b>Nanotechnology.</b>
		+	*<b>Engineering the minimal cell.</b> Scientists are trying to identify or build a cell that contains only those elements necessary to be able to classify it as "living." Bot top-down (Venter) and bottom-up (Luisi) approaches are being used. This research could shed light on the earliest origins of life, as well as provide a vessel for engineering synthetic biological functions that avoids the variables typically encountered when introducing a synthetic pathway into a cell.
		+	*

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 Students in the synthetic biology seminar each chose a topic in synthetic biology on which to write a paper. With our selections, we do not claim to cover all aspects of synthetic biology but instead to provide an overview on subjects we found interesting.  The topics we chose can be classified within three broader areas of synthetic biology research:
-#<b>Designng and Optimizing Tools.</b> Papers by Mike, Laura, Hunter
+#<b>Designng and Optimizing Tools.</b>  Mike, Laura, Hunter
-#<b>Small Parts and Devices.</b> Papers by Erin, Emma, Danielle
+#<b>Small Parts and Devices.</b>   Erin, Emma, Danielle
-#<b>Broader Applications.</b> Papers by Samantha, Will
+#<b>Broader Applications.</b>  Samantha, Will