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| − | Halomicrobium mukohataei:
| + | == Phylogenetic Tree == |
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| − | CRISPR-associated protein Cas2 at complement(1004454..1004717)<br>
| + | [[Image:phylogram.png]] |
| − | MVYVVVVYDMEADRTHKMLKFLRRYLTHVQNSVLEGDVTEGDLEKIRSGVDDLLKPGESTIIYQISSEKLVDRSVFGDDPA<br>ADDQFL
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| − | > CRISPR-associated protein Cas1 at complement(1004721..1005719)<br>
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| − | MIMNDNYHVFSDGRIERHDDTVRVITDDGEKKYLPVENAEAIFLHGQIEYNTRFVSFLNQEGVAVHVFGWHDHYAGSIMP<br>KRGQTSGQTLVDQVRAYDDPAHRLELAQAFVDGSIHNMRANVTYYDGRGHDFEDVLAELTEARSSLDRMETIDET<br>MGVEARARKAYYSTFDEILPDEFVFGGRQYDPPNNEVNSLISFGNSLVYANVVSAIRATALDPTVSFLHEPGERRYSLA<br>LDIADLFKPLLADRVIFRLVNRGQLTSDDFEAEMNACLLNEHGRKTYSKAYEETLDETIEHPDLGKKVSYQYLLRVEV<br>YKLKKHLLTGEEYVPFQRWW
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| − | > CRISPR-associated RecB family exonuclease at CAYHDFCWSC"<br>
| + | [[Input that WORKS!]] |
| − | MTDSSGDPVDRFLAAARDESAELPFRLTGVMFQYYVVCERELWFLSRDVEIDRDTPAIVRGSDVDDSAYADKRRDVRVDGI<br>IAIDVLDSGEILEVKPSSSMTEPARLQLLFYLWYLDRVTGVEKTGVLAHPAEKRRETVELTPETSAEVESAIEGIRAVV<br>
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| − | > CRISPR-associated helicase Cas3 at complement(1006273..1008843)<br>
| + | ==CRISPR-associated Protein Alignments == |
| − | MGTEPISHPATDGDEATRLLDHLDDVAGRAESVVSADATTIGGDPLPEMTAVVARCHDFGKATTWFQAYVVGERDASDR<br>TNHSLLGAYLGYYVLDRLGYDSEDCLAALVALAKHHGQLPDVEEYVDGVSRFENTSEASNERQRILIEQVGNVDDH<br>RRQFAQSFVADATDGNGSWEEFAQSIEDESLFDTVHEHVSLFGFGSDRSAPSEEFYGLLLQLWSGLVFADKTVAAGIE<br>NGDLDGSEPDARLLSEYIADLGGDTDEDGQAAALDTLRGEARDDVLGGVERFRDSEVSIATLTLPTGMGKTLTGLS<br>AALALRDEGERVVYALPFTSVIDQVADELADVFDTDARDDLLTIHHHLAETVTKLGDPDEDPDEYARLAEMVAESW<br>RSGMTLTTFVQLFESLVGPSNTQSMKLPALYDSVIVLDEPQALPMQWWKLVRRIATILTEEYDATIVAMTATQPRAT<br>DEETASQALFDDAFELVDDVDRYFGHFERVEYDVHDSVLAFDDTDAIVDYETAGRTILDETGRSESTLAICNTIDSAT<br>ALTDAIEEREAVVDVGRCLELELDDGADVDALVERVESTLSSNERALVHLSTRLRPRDRLALVEATKRLTERDVPVLA<br>VSTQLIEAGVDISFDRVYRDIAPIDSVVQAAGRCNRSFESDLGTVTVWWLAPPAGTTTTPAQAVYDSEGVSTISLTAR<br>TLDAIGADDGTVAEQTMTRDAVEHYYGLVADRNPGDPEYVKWVDEANADALGGLSLIGQRESVDVVVCRTDGDR<br>ELADAMVAALDEFDYDAFGDYREAAKDITVSLPIYSRDSTEAETVRNLEPLGDADLRVLRRARGTSYFDETKGLAVD<br>EPCVDDRFL
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| − | > CRISPR-associated protein, TM1800 family at complement(1008843..1009520)<br>
| + | '''Cas1 Protein Comparison:''' |
| − | MKQTYRVIPRTTVAGLIAAMLGIERDGYYDLFAPGESLVAIEPTSELRTMKLPMNTLSTADEHMASLNPRGKLSIKLPDPSKP<br>RQQHNYEVLVEPAYRIDVWLADDERYDRLRSLLESGESYYVPSLGLSEHLATIDYHGEFPVEHGPDGETVAIDSTVPE<br>AVDSIVPDPETRYQIEQTPAFMERDDGGRTTSAFVSYAYNPDGGSLRVADVSTYSVDDRAVVFT<br>
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| − | > CRISPR-associated protein, TM1801 family at complement(1009635..1010690)<br>
| + | [[Image:Cas1align.png]] |
| − | MSEHYPTVSNRSEIVFAYDAVDANPNGNPLSGANRPRIDPHTDQAIVTDVRLKRYLRDQLQDDGHGVYIRNVKEDDGDQ<br>ATREDLLEDRLKDIDLDDVDEADIENAVFGQFLENSADVRYFGATMSIDMDDEKVDHLPDHFTGPVQFSPGKSLHR<br>VMENEEYNSLTSVIATGDDKAQGGFDLDDHRIQYAFIGFHGLVDEHGAEGTLLTDGDVRRLDTLCWRALKNQTISR<br>SKVGQEPRLYLRVEYADESFHLGGLDQDIDLDSSESAPVEEIRNVRDICVDVSALLERLDAASDRIDTVHVVASDVLEL<br>SVDGETGGPEFLYDALESRVGSESVREIDVYEDAKATMPEE
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| − | Haloarcula californiae:
| + | '''Cas2 Protein Comparison:''' |
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| − | > CRISPR-associated helicase Cas3 at complement(1844..4447)<br>
| + | [[Image:Cas2align.png]] |
| − | MTFEQYISHPAKTDDGEPTLLIGEGGQFDQDGHLQTVANRMVEACRGQTLADGTPAEPVAEVIGLTHDFAKLTHWAQKH<br>LRCQPFQHSDEYRYHAFPGALVTLYCLLNRRDGTGPLKDDHAAEVATLVVAGHHDIQSPPEPSKLAKNYGRDTLEV<br>QETYKRITEQFEDIGDRVPERADQIIHKATDGEGSWEDFREWHADRTAPIDGPHHHLIYFAQIGDRDTRDGYYSDVV<br>RLWTALKFADQTDASGLKNEDIGGTLLDRSELTRHIEDLDKGENVLAELNDLRNKARQEVTENVETLVKSNDVGLIT<br>LPTGFGKTYAGISAGLRAANINDSRLVYALPYTSILDQTASEIQSVFGVSPYSRAFTLHHHLSNTYTGLGDHYTDADI<br>GRSPGALHAESWLSGVTLTTTVQLFESLAAPTARQATRVPALHEAVVVIDEPQAIPEDWWQIIPELVELLVDSYNATVI<br>LMTATQPGLVKYGSNTLNTRELTDATDKYTDFLADHPRVRYRLHDTVRTDVGDEYATLDYATAGSRVSGAAEGG<br>RDVLAVCNTRASAEELYRSVTATVNTKEKVPVELGHLLHDYVEETGELPSPVELRRFAIDAVAERDVATLYAFLSGDV<br>RPDDRKLIIDTLYDDEIGDEDEPEPLLDSDWSVILVSTSVVEAGVDVSFDTVFRDYAPIPNIVQSGGRCNRSFDGETGD<br>VVVWRLAEPENGSAIPSLVIHGADGGDQLPLLLATGNVLRRHAARDGTIDESTMVSDTVSEFYESLFEGPLNPGNERL<br>ADAISSASMSELEGEHMIDEIEDYEDVVACLTDEERDDLLSSDPEAVSIRGHPGAQVSTDLEAWTKKVTIGNSQYLLV<br>DALSGSYHPVFGVR
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| − | > CRISPR-associated protein, TM1800 family at complement(4458..5279)<br>
| + | '''Cas3 Protein Comparison:''' |
| − | MTQQDLTDYASEGGDSSSSRYIPDTCIGFDVTADFAHFRKVGNNSAKPSYRIPPRTTVAGLLAGILGMPRDSYYDLFSPARS<br>AIAIVPKGLPHTYTMGITTVNTKADDAIQYLPQEKHYTKSAEMLTPESYVKYDRQRDTYEMLVDPEYRVYVALSDQN<br>SYNELRERLETSRYHYSPALGLSECIADIRNVEIHTVGPGIEDAVDSAAYDDSEVVPKPGVTIKRERAPLYMESTDGGR<br>RTTEFGNITYAAGDDRLPVDESRTHTVGEHQVAFY
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| − | > CRISPR-associated protein, TM1801 family at complement(5304..6332)<br>
| + | [[Image:Cas31.png]] |
| − | MTDTNDATIQNRSEIAFVIDAKDTNPNGDPLTADNEPRIDPVTGQCVVTDVRLKRYLRDQLVEDDHVVLIANPNDEVLTR<br>KEMYDAVESEMGVSTDEAEPEELLEAFVKTAADVRYFGATISLDTDLAEDLPNQFEGPVQFNHGRSYHEVARNTESK<br>QLATVIANEDDDGGKKDQGTFATDNRISYGVIGFGGRINDNAAKDTHLTEDDVERLDTLCWRALKNQTVTRSKAG<br>QQPRLYIRVEYKQDGFEIGRLNDRIGVDSDLPEDEIRGTDDFNLDVSELVTTLADNDARIDTVHITADSAVTFALPDG<br>ETGDREALYTVLNDILGAEAVDAYDVYERYVN
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| | + | [[Image:Cas32.png]] |
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| | + | [[Image:Cas33.png]] |
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| | + | '''Cas4 Protein Comparison:''' |
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| | + | [[Image:Cas4align.png]] |
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| | + | '''Cas1800 Protein Comparison:''' |
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| | + | [[Image:Cas1800align.png]] |
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| | + | '''Cas1801 Protein Comparison:''' |
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| | + | [[Image:Cas1801align1.png]] |
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| | + | [[Image:Cas1801align2.png]] |
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| | + | [[Protein Sequences for Cas-proteins]] |
