Difference between revisions of "Evolved Stochasticity?"
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− | |<center>Stochasticity has also been theorized to | + | |<center>Stochasticity has also been theorized to have implications in disease and development. While significant results are still pending, haploinsufficiency diseases are thought to arise in part from stochasticity in gene expression. This is becuase the single functional allele cannot produce the amount of protein needed to keep the body's respective concentration continually above a low threshold state due to the pulsitile nature of mRNA production. Stochasticity may also play a role in stem cell differentiation. Stochasticity initially establishes heterogenity within an initially homologous population that allows for the selection of cell-type-specific gene expression and eventually differentiation(). |
In the study of stochasticity and gene expression the obvious question seems to be: Why are certain processes so noisy? From an evolutionary standpoint it seems counterinutive that natural selection would allow complex systmes to exhibit protein expression behavior that is variable and unpredictable. </center> | In the study of stochasticity and gene expression the obvious question seems to be: Why are certain processes so noisy? From an evolutionary standpoint it seems counterinutive that natural selection would allow complex systmes to exhibit protein expression behavior that is variable and unpredictable. </center> | ||
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Revision as of 17:37, 13 November 2007
In Depth | Is Phenotypic Noise a Product of Natural Selection? | ||
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