Difference between revisions of "NHE Jan 19 Notes"
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(Created page with "http://www.bio.davidson.edu/courses/Bio343/2016/2a_peptides_hormones_2001.pdf http://www.bio.davidson.edu/courses/Bio343/2016/2b_adaptive_digestion_2007.pdf Regulato...") |
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*we hypothesize that active eating activates hormone response; looking early on, hours after eating | *we hypothesize that active eating activates hormone response; looking early on, hours after eating | ||
*enzymes need to make the hormones and then we need the receptors | *enzymes need to make the hormones and then we need the receptors | ||
| − | + | **plasma membrane or cytoplasm | |
*some of the mammalian antibodies cross react - no the intended target | *some of the mammalian antibodies cross react - no the intended target | ||
*used column chromatography to try to identify reptilian versions of synthetically produced human homologs | *used column chromatography to try to identify reptilian versions of synthetically produced human homologs | ||
Revision as of 19:53, 19 January 2016
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Regulatory Peptides (2001)
- lots of hormones and peptides
- intestine changes before the meal reaches it
- we hypothesize that active eating activates hormone response; looking early on, hours after eating
- enzymes need to make the hormones and then we need the receptors
- plasma membrane or cytoplasm
- some of the mammalian antibodies cross react - no the intended target
- used column chromatography to try to identify reptilian versions of synthetically produced human homologs
Adaptive Regulation (2007)
- Fig 1. ever letter is sig. dif. from other letters
- change in intestine mass is from hypertrophy - cells grow bigger, not replication
*cell division increased, but so did apoptosis
- enterocytes increase volume
- transport proteins may already exist in intracellular membranes that are then released to the luminal membrane
- would not result in a peak in RNA transcription
- part of why the cells are fatter is because they cells are full of lipid droplets
*endocytosis - not actively transported
