Difference between revisions of "Modeling Promoter Activity"
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In order to use synthetic promoters to their fullest potential, we have to understand how they work. Sythetic promoters cannot help us model gene circuit activity unless models are developed for the activity of the promoter itself. Determining how exactly a promoter's strength correlates to its mutations is not easy, since for the most part it requires working with promoters on the level of individual sets of nucleiotides. | In order to use synthetic promoters to their fullest potential, we have to understand how they work. Sythetic promoters cannot help us model gene circuit activity unless models are developed for the activity of the promoter itself. Determining how exactly a promoter's strength correlates to its mutations is not easy, since for the most part it requires working with promoters on the level of individual sets of nucleiotides. | ||
| − | === Jensen and Hammer ( | + | === Jensen and Hammer (1997): Spacer Sequences === |
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=== Jensen, Alper, Fischer, and Stephanopoulis (2006): Statistical Modeling and Critical Mutation Sites === | === Jensen, Alper, Fischer, and Stephanopoulis (2006): Statistical Modeling and Critical Mutation Sites === | ||
Revision as of 20:17, 6 December 2007
Contents
Modeling Promoter Activity
In order to use synthetic promoters to their fullest potential, we have to understand how they work. Sythetic promoters cannot help us model gene circuit activity unless models are developed for the activity of the promoter itself. Determining how exactly a promoter's strength correlates to its mutations is not easy, since for the most part it requires working with promoters on the level of individual sets of nucleiotides.
