WEEK THREE (January 30 - February 3)

We have an X-prize type of challenge for you.

We are wondering if there are a set of type IIs restriction enzymes (also see RE Base) within which you could embed other type IIs restriction site(s) to do something useful or interesting. Perhaps you could improve upon Golden Gate assembly, or other methods in the paper reviewed by Becca Tom Ellis Tom Adieac and Geoff S. Baldwin. Or perhaps you can think of a way to represent a mathematical problem with combinations of sites.

You can work solo or in teams of your design. However, everyone must participate in this challenge.

Ethics paper for discussion in large group (all read):

Talking the Talk
Colin Mcilswain
Nature. Vol 465, page 867.

Paper Presentations for Week Three:

Team 1 MONDAY = Alex, Nishita, Erich
Noise in Gene Expression: Origins, Consequences, and Control
Jonathan M. Raser and Erin K. O’Shea
Science. Vol. 309, page 2010

Team 2 TUESDAY = Ellen, Dancho, Kirsten
Synthetic Biology: Integrated Gene Circuits
Nagarajan Nandagopal and Michael B. Elowitz
Science. Vol. 333, page 1244.

Team 3 WEDNESDAY 2:30 pm = Duke, Becca, Ben
Network Motifs: Simple Building Blocks of Complex Networks
R. Milo, S. Shen-Orr, et al
Science. Vol. 298, page 824.

Everyone FRIDAY 3:00 pm (one-time delayed start)