NHE Jan 19 Notes
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Revision as of 19:53, 19 January 2016 by Nielder (talk | contribs) (Created page with "http://www.bio.davidson.edu/courses/Bio343/2016/2a_peptides_hormones_2001.pdf http://www.bio.davidson.edu/courses/Bio343/2016/2b_adaptive_digestion_2007.pdf Regulato...")
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Regulatory Peptides (2001)
- lots of hormones and peptides
- intestine changes before the meal reaches it
- we hypothesize that active eating activates hormone response; looking early on, hours after eating
- enzymes need to make the hormones and then we need the receptors
*plasma membrane or cytoplasm
- some of the mammalian antibodies cross react - no the intended target
- used column chromatography to try to identify reptilian versions of synthetically produced human homologs
Adaptive Regulation (2007)
- Fig 1. ever letter is sig. dif. from other letters
- change in intestine mass is from hypertrophy - cells grow bigger, not replication
*cell division increased, but so did apoptosis
- enterocytes increase volume
- transport proteins may already exist in intracellular membranes that are then released to the luminal membrane
- would not result in a peak in RNA transcription
- part of why the cells are fatter is because they cells are full of lipid droplets
*endocytosis - not actively transported
