Difference between revisions of "Combinatorial promoter design for engineering noisy gene expression"
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==Math== | ==Math== | ||
| − | Dose-response Curve | + | '''Dose-response Curve'''<br> |
| − | The Dose-response relationship describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical). This may apply to individuals (eg: a small amount has no observable effect, a large amount is fatal), or to populations (eg: how many people are affected at different levels of exposure). (from wikipedia) | + | The Dose-response relationship describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical). This may apply to individuals (eg: a small amount has no observable effect, a large amount is fatal), or to populations (eg: how many people are affected at different levels of exposure). (from wikipedia) <br><br> |
| − | + | Dose-response curves are often modeled by the Hill function <br> | |
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| + | [http://www.fasebj.org/cgi/content/abstract/11/11/835 Helpful characterization of the uses of the Hill function]] | ||
==Building Blocks== | ==Building Blocks== | ||
| − | + | [[Gal10 Gal1 system]] <br> | |
| − | + | ==Online Supplemental Material== | |
| + | [http://www.bio.davidson.edu/Courses/Synthetic/papers/MWappendix.pdf Appendix] | ||
Latest revision as of 03:57, 22 September 2007
Math
Dose-response Curve
The Dose-response relationship describes the change in effect on an organism caused by differing levels of exposure (or doses) to a stressor (usually a chemical). This may apply to individuals (eg: a small amount has no observable effect, a large amount is fatal), or to populations (eg: how many people are affected at different levels of exposure). (from wikipedia)
Dose-response curves are often modeled by the Hill function
Helpful characterization of the uses of the Hill function]
