Difference between revisions of "Noise in Feedback Loops"
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| − | Some gene networks engage in the production of autoregulatory proteins. | + | Some gene networks engage in the production of autoregulatory proteins. Collins details that an experiment run by Beckskei and Serrano characterized the effect of a negative feedback loop on noise in genetic autoregulatory networks. Becskei and Serrano generated a regulatory network and tested the noise strength in the absence of its negative feedback loop. The comparison between the two states revealed that negative-autoregulation reduces noise in an autoregulatory system. |
| + | Collins also detailed that the usual outcome of positive-feedback regulation is bistability because it gives rise to cellular states of high and low expression levels (Collins ''et. al.'', 2005). | ||
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<center>[[Manipulation of Stochasticity | Return to Manipulation of Stochasticity]] </center> | <center>[[Manipulation of Stochasticity | Return to Manipulation of Stochasticity]] </center> | ||
Latest revision as of 16:04, 10 December 2007
Some gene networks engage in the production of autoregulatory proteins. Collins details that an experiment run by Beckskei and Serrano characterized the effect of a negative feedback loop on noise in genetic autoregulatory networks. Becskei and Serrano generated a regulatory network and tested the noise strength in the absence of its negative feedback loop. The comparison between the two states revealed that negative-autoregulation reduces noise in an autoregulatory system. Collins also detailed that the usual outcome of positive-feedback regulation is bistability because it gives rise to cellular states of high and low expression levels (Collins et. al., 2005).
