Difference between revisions of "Noise in Feedback Loops"
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| − | Some gene networks engage in the production of autoregulatory proteins. | + | Some gene networks engage in the production of autoregulatory proteins. Collins details that an experiment run by Beckskei and Serrano characterized the effect of a negative feedback loop on noise in genetic autoregulatory networks. Becskei and Serrano generated a regulatory network and tested the noise strength in the absence of its negative feeedback loop. The comparision between the two states revealed tath negative-autoregulation reduces noise in an autoregulatory system. |
| − | + | Collins also detailed that the usual outcome of positive-feedback regulation is bistability becuase it gives rise to cellular states of high and low expression levels. | |
<br><br><br> | <br><br><br> | ||
<center>[[Manipulation of Stochasticity | Return to Manipulation of Stochasticity]] </center> | <center>[[Manipulation of Stochasticity | Return to Manipulation of Stochasticity]] </center> | ||
Revision as of 03:58, 13 November 2007
Some gene networks engage in the production of autoregulatory proteins. Collins details that an experiment run by Beckskei and Serrano characterized the effect of a negative feedback loop on noise in genetic autoregulatory networks. Becskei and Serrano generated a regulatory network and tested the noise strength in the absence of its negative feeedback loop. The comparision between the two states revealed tath negative-autoregulation reduces noise in an autoregulatory system.
Collins also detailed that the usual outcome of positive-feedback regulation is bistability becuase it gives rise to cellular states of high and low expression levels.
