Origins and Characterization of Stochasticity
From GcatWiki
In Depth | Overview of the Origins and Characterization of Stochasticity | ||
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Finite Number Effect
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A Prokaryotic vs. a Eukaryotic background is an important distinction to make when characterizing stochasticity. Differences in transcriptional and translational processes lead to differences in dominant manifestations of non-genetic identity. In prokaryotes Ozbudak et. al. characterized a modular model of expression noise in prokaryotic Bacilus Subtillis. In his model transcription and translation were two sources of stochasticity. JJ Collins et. al. suggested that promoter kinetics were also a factor depending on the system. The significance of stochastic events truly depends on the nature of the system. |