Origins and Characterization of Stochasticity
In Depth | Overview of the Origins and Characterization of Stochasticity | ||
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Finite Number Effect
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A Prokaryotic vs. a Eukaryotic background is an important distinction to make when characterizing stochasticity. Differences in transcriptional and translational processes lead to differences in dominant manifestations of non-genetic identity. In prokaryotes Ozbudak et. al. characterized a modular model of expression noise in prokaryotic Bacilus Subtillis. In his model transcription and translation were two sources of stochasticity. JJ Collins et. al. suggested that promoter kinetics were also a factor depending on the system. The abundance of characterizations of noise and backgrounds suggests that the significance of stochastic events truly depends on the nature of the system. This is not to say that that stochastic events cannot be predicted and taken into account. |