Stochasticity in a Eukaryotic Background
From GcatWiki
The transcriptional processes in Eukaryotes are different from prokaryotes. The differences in Eukaryotic gene expression ultimatly emphasizes different sources of stochasticty as singinicant sources of noise. The need for Eukaryotic genetic information to transition between open and closed chromatin structures makes the turnover time from and induced to a repressed promoter very slow. () Demonstrated that transcriptional efficiency has a larger effect on noise strength than translational efficiency in Eukaryotes.
Other Factors in Eukaryotic Backgrounds
- Transcriptional initiation involves TATA box binding protein
- Initiated mRNA forms a stable complex
In addition to chromatin remodeling
