Translational Bursting

Translational Bursting is the Main Source of Stochasticity in Prokaryotes

The amount of protein translated per strand of mRNA produced is a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. The variable mRNA concentration results in a more noise in the expression of proteins. Tranlational bursting is suggested to be the main source of translational bursting in prokaryotes; the finite number effect has a larger influence over mRNA levels than protein levels.

Results

()1 figure for translational bursting () figure for how TB is better than FNE