Translational Bursting

Translational Bursting is the Main Source of Stochasticity in Prokaryotes

The amount of protein translated per strand of mRNA produced is a transcripts translational effciency or "burst parameter". Proteins are translated from mRNA in a pulsatile manner often described as "short bursting". Genes that are regulated by operons with low translational efficiency have a lower amount of noise than those exhibiting high translational efficiency. This is becuase a lower amount of mRNA in the cell means that the concentration of mRNA's be more susceptible to stochastic events such mRNA degredation. The variable mRNA concentration results in a more noise in the expression of proteins. Tranlational bursting is suggested to be the main source of translational bursting in prokaryotes; the finite number effect has a larger influence over mRNA levels than protein levels.

Factors that Influence Translational Bursting

Degredation, get there when you come to it.

Results

()1 figure for translational bursting () figure for how TB is better than FNE