Difference between revisions of "Vocabulary"
| Line 1: | Line 1: | ||
| − | 5mCpG | + | '''5mCpG''' |
| − | Androgenic hydatidiform mole | + | '''Androgenic hydatidiform mole''' |
| − | Bisulfite conversion | + | '''Bisulfite conversion''' |
| − | Capillary electrophoresis | + | '''Capillary electrophoresis''': a technique that separates DNA fragments amplified by PCR according to their electrophoretic mobility |
| − | CpG Islands/Sites | + | '''CpG Islands/Sites''' |
'''DMR''':differentially methylated region; stretches of DNA in an organism’s genome that have different DNA methylation patterns compared to other samples | '''DMR''':differentially methylated region; stretches of DNA in an organism’s genome that have different DNA methylation patterns compared to other samples | ||
| − | gDMR | + | '''gDMR''' |
| − | hESC | + | '''hESC''' |
'''HhaI''': a methylation sensitive restriction enzyme that won’t cleave DNA in methylated region. | '''HhaI''': a methylation sensitive restriction enzyme that won’t cleave DNA in methylated region. | ||
| − | ICR | + | '''ICR''' |
| − | MSRE-PCR | + | '''MSRE-PCR''' |
'''MT21''': nuclear family trio with Down syndrome of maternal origin | '''MT21''': nuclear family trio with Down syndrome of maternal origin | ||
| Line 35: | Line 35: | ||
'''PT21''': nuclear family trio with Down syndrome of paternal origin | '''PT21''': nuclear family trio with Down syndrome of paternal origin | ||
| − | rs# | + | '''rs#''': “Reference SNP” - way to reference specific SNPs (Single Nucleotide Polymorphisms) |
'''SNP''': single nucleotide polymorphisms; difference in a single nucleotide at a specific position; the most common type of genetic variation among people | '''SNP''': single nucleotide polymorphisms; difference in a single nucleotide at a specific position; the most common type of genetic variation among people | ||
Revision as of 14:59, 24 January 2017
5mCpG
Androgenic hydatidiform mole
Bisulfite conversion
Capillary electrophoresis: a technique that separates DNA fragments amplified by PCR according to their electrophoretic mobility
CpG Islands/Sites
DMR:differentially methylated region; stretches of DNA in an organism’s genome that have different DNA methylation patterns compared to other samples
gDMR
hESC
HhaI: a methylation sensitive restriction enzyme that won’t cleave DNA in methylated region.
ICR
MSRE-PCR
MT21: nuclear family trio with Down syndrome of maternal origin
N21:"normal" nuclear family trio without Down syndrome
NCBI GEO Nondisjunction
Oogenesis: The development of a mature egg cell (ovum) from the primary oocyte.
Proband: A person that is used as the starting point for a family in a genetic study. A term used especially in medicine or psychiatry.
PT21: nuclear family trio with Down syndrome of paternal origin
rs#: “Reference SNP” - way to reference specific SNPs (Single Nucleotide Polymorphisms)
SNP: single nucleotide polymorphisms; difference in a single nucleotide at a specific position; the most common type of genetic variation among people
SNuPE SRA
STR: Short tandem repeats. A region of the DNA two-thirteen bases long that is repeated up to hundreds of times. These regions can be used to trace lineage
TSS
WRB: Tryptophan Rich Basic Protein coding gene. This gene codes for a nuclear protein of unknown function. Known as a critical region for Down Syndrome because it is linked to congenital heart disease and heart disease.
