Difference between revisions of "January 26, 2016"
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| − | + | == Article Discussion == | |
| + | === "Rapid Changes in Gene Expression Direct Rapid Shifts in Intestinal Form and Function in the Burmese Python after Feeding" (2015) === | ||
| + | *Provides the names of specific genes involved in the postprandial response of Pythons. | ||
| + | *Lots of genes change expression levels within the first 6 hours post-feeding. | ||
| + | *Introduces the potential involvement of the WNT signaling pathway. | ||
| + | *The anterior third of the Small Intestine experiences the most differential gene expression. | ||
| + | *Cell death and growth are occurring. | ||
| + | *The NIH provided funding for this project because understanding the genes and mechanisms involved in the postprandial adaptations of Pythons could have the potential to enhance treatment of human diseases. | ||
| + | |||
| + | |||
| + | === Questions to Consider: === | ||
| + | *How different will the genes from our sample (30 minutes) be from the sample (6 hours) of the Andrew et al. (2015) study? | ||
| + | *Can we compare our number of reads to the Andre et al. (2015) study number of reads? | ||
| + | *Can we get the names of the genes? | ||
[http://gcat.davidson.edu/mediawiki-1.19.1/index.php/Ashlyn Ashlyn's Main Page] | [http://gcat.davidson.edu/mediawiki-1.19.1/index.php/Ashlyn Ashlyn's Main Page] | ||
| + | |||
| + | |||
| + | |||
| + | |||
| + | <big>''References"</big> | ||
| + | |||
| + | *Andrew, Audra L., et al. “Rapid changes in gene expression direct rapid shifts in intestinal form and function in the Burmese python after feeding.” Physiol Genomics. 47 (2015): 147-157. | ||
| + | :::[http://www.bio.davidson.edu/Courses/Bio343/2016/4a_Todd%20Castoe%20Python%20RNAseq_2015.pdf Andrew et al. (2015)] | ||
Latest revision as of 16:47, 13 February 2016
Article Discussion
"Rapid Changes in Gene Expression Direct Rapid Shifts in Intestinal Form and Function in the Burmese Python after Feeding" (2015)
- Provides the names of specific genes involved in the postprandial response of Pythons.
- Lots of genes change expression levels within the first 6 hours post-feeding.
- Introduces the potential involvement of the WNT signaling pathway.
- The anterior third of the Small Intestine experiences the most differential gene expression.
- Cell death and growth are occurring.
- The NIH provided funding for this project because understanding the genes and mechanisms involved in the postprandial adaptations of Pythons could have the potential to enhance treatment of human diseases.
Questions to Consider:
- How different will the genes from our sample (30 minutes) be from the sample (6 hours) of the Andrew et al. (2015) study?
- Can we compare our number of reads to the Andre et al. (2015) study number of reads?
- Can we get the names of the genes?
References"
- Andrew, Audra L., et al. “Rapid changes in gene expression direct rapid shifts in intestinal form and function in the Burmese python after feeding.” Physiol Genomics. 47 (2015): 147-157.
