Aspartate Carbamoyltransferase

I did a blastp search using our species' ACTase protein sequence, the following where the results. . .

Halophilic Species with Protein Similarity

Haloarcula marismortui protein sequence:

  >Haloarcula marismortui ATCC 43049
MRHDHIISAKQLSRGDIETVLDHAADIAADPGAFADRHSDTLLGLLFFEPSTRTKMSFTTAMKRLGGDIV
DMGSVESSSVKKGESLADTVRVVEGYTDALVLRHPMEGSAKMASEFVDVPLVNAGDGAGQHPTQTLLDLY
TIRENAGFDDLTIGIMGDLKYGRTVHSLAHALTTVDASQHFISPESLQLPRSVRYDLHEAGAGIREHTEL
DDILPELDVLYVTRIQAERFPDESEYREVAGQYQIDGDTLAAAKDDLTVMHPLPRVDEIAHDVDETTHAQ
YFQQAHNGVPVRMALLDLMLGGDQ

Halorhabdus utahensis protein sequence:

>Halorhabdus utahensis DSM 12940
MRHDHIISAKQLSRSDIEEVLDRAAEIARDPTAFRQRHPGALLGLLFFEPSTRTKMSFSASIKRLGGDIV
DMGPVEYSSVKKGESLADTVRVVEGYADALVLRHPMEGSAKMASEFVDVPLINGGDGAGQHPTQTLLDLY
TIRENAGLDDLSIGIMGDLKYGRTVHSLAHALTNFDASQHFISPESLRLPRNVRYDLHEEGATIREHTAL
DTVLDSLDVLYVTRIQEERFPEESEYRKVAGEYRIDAETLESTRDDLTVLHPLPRVDEIDHDVDATSHAQ
YFQQAHNGVPVRMALLDLVLGGESA

Natronomonas pharaonis- got rid of this because i did not want to introduce differences from other

>Natronomonas pharaonis DSM 2160]
MRHDHLLSAKQLSRGDIEGVLDRAAEIAADPDAVAEKHSDKLLGLLFFEPSTRTKMSFDTAMKRLGGDTV
DMGSVDSSSVKKGESLADTVRVIEGYTDAIVLRHPSEGSPKLASEFVDVPVINAGDGAGQHPTQTLLDMY
TIRENAGLDDLTIGIMGDLKYGRTVHSLAHALTNFDVSQHFISPESLQLPRSVRYDLHESGAQVREHTDI
ESVLETLDVLYVTRIQRERFPDENEYRQVAGEYRIDADLLESAKDDLTVMHPLPRVSEIAADVDETEHAT
YFKQAHNGVPVRMALLDEML

Halorubrum lacusprofundi

>Halorubrum lacusprofundi ATCC 49239]
MRQDHLITATQLSRDDIEAVLDRAREVADDPAAYADRHAGSVLALCFFEPSTRTRMSFDSAAKRLGMNTI
GMGDVDSSSVSKGESLSDTVRVIEGYADALVLRHPSEGAATLAAERVSVPVVNAGDGAGQHPSQTLLDLH
TIRENHGLDDLTVGIMGDLKYGRTVHSLAAALTEFDANQHFISPESLRLPRSVRFDLHETGAQVREHTDL
EGVLGELDVLYVTRIQKERFPDENEYHRVAGEYQIDAETLEDAPDDLTVMHPLPRVDEIAPDVDETDHAT
YFEQAHNGIPVRMALLDILLENAEGDEGMEVDR

Halobacterium salinarum

>Halobacterium salinarum R1]
MDLDHIITSKQLSRADIETVLDRAAEIDADPSAFADRYENTVLGLLFFEPSTRTKMSFDTAMKRLGGDIV
DMGSVDSSSVKKGETLADTVRVIEGYADALVLRHPNQGAAQMASEFVDVPLLNAGDGAGHHPTQTLLDLY
TIRENAGLEDLTIGIMGDLKYGRTVHSLSRALTNFDVDQHFISPESLQLPRDVVYDLEQESGTRVREHDS
FEDVLPELDILYVTRIQRERFPDENEYQKVAGEYQLTATHLEAAKDDLTIMHPLPRVDEIAPEIDDTDHA
AYFEQAHNGVPVRMALLDLVLSADGGVDDE

Halogeometricum borinquense

>Halogeometricum borinquense DSM 11551]
MRQDHLISATQLSRDDVEAVLDRAADIDADPAAWRQRHAGTVLGLCFFEPSTRTRMSFDTAMKRLGGRTV
DMGPVESSSVKKGESLADTVRVVEGYGDAIVLRHPLEGAAKMASEFVDVPVINAGDGAGQHPTQTLLDLY
TIRENAGLDDLTIGIMGDLKYGRTVHSLAEALTNFDARQHFISPESLRLPRNVRYDLHGSGAQVREHTEL
SEVLPELDVLYVTRIQRERFPDENEYRKVAGQYQIDADDLSDAKDSLTVMHPLPRVDEIAPEVDETAHAK
YFEQAHNAVPVRMALLDMLLEDN

Natrialba magadii- got rid of because i wanted to narrow search to just salt-loving and not other extremophiles

>Natrialba magadii ATCC 43099]
MRHDHLITSKQLSRADIETVLDRAAEIADDPDAVANRHANAVLGLLFFEPSTRTKMSFETAMKRLGGSVV
DMGSVESSSVKKGETLADTVRVIEGYADSLVLRHPKQGAAAMACEFVDVPLLNAGDGAGHHPTQTMLDLY
TIRENAGLDDLTIGIMGDLKYGRTVHSLSYALTNFDTHQHFISPESLQLPREVVYDLHQQDDTQIREHEA
LESVLPSLDVLYVTRIQRERFPDENEYQKVAGEYQIDLETLEDASDDLTIMHPLPRVDEIAPEIDETEHA
AYFEQAHNGVPVRMALLDLLLSGGETDE

Haloquadratum walsbyi

>Haloquadratum walsbyi DSM 16790]
MHQDHLLSTTQLSREDIETILDRAAAIEMNPDGWEAQYSGTVLGLCFFEPSTRTRMSFDAAMKRLGGRTI
DMGSVDNSSISKGETLADTVRVIAGYADAIVLRHPSEGAAKLAAEFVDIPVINAGDGAGQHPTQTLLDLY
TMRENVGLDEITVGIAGDLKYGRTVHSLAAALSNFDVRQHFISPESLQLPRNIRYDLHDSGSQVREHTDI
ESILPELDVLYVTRIQRERFPDENEYQRVAGQYRVDTDILSHADNNLTVMHPLPRVDEIAPEVDTTEHAA
YFEQAHNGVPVRMALLDALIGRAK

Marine Bacterium

Vibrio parahaemolyticus

>Vibrio parahaemolyticus AQ3810]
MSKIPQRSILEIVITVIGKKIMANSLYQKHIISIPELSREELELIVETAGNLKKEPRPELIKNKVVASCF
FEPSTRTRLSFETAIQRIGGDVIGFDNDGNTSLAKKGETLSDSVQVISSYVDAFVMRHPQEGAARLASEF
SNGVPVINAGDGANQHPTQTLLDLYTIAETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFYFVA
PDALAMPEYICEELDEAGIEYSLHTEMEAVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLKGAR
ENLKVLHPLPRVDEITTDVDKTPHAYYFQQAQNGVYARQALLALVLNETL

Vibrio harveyi

>Vibrio harveyi HY01]
MANSLYQKHIISIPELSREELELIVETAGQLKKEPRPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGD
VIGFDNGGNTSLAKKGETLSDSVQVISSYVDAFVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTL
LDLYTIAETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFFFVAPEALAMPDYICEELDEAGIQY
SLHTDMESVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLEGARENLKVLHPLPRVDEITTDVDV
TPHAYYFQQAENGVYARQALLALVLNETL

Vibrionales bacterium

>Vibrionales bacterium SWAT-3]
MANSLYQKHIISIPELSREELELIVQTAGQLKAEPNPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGD
VIGFDSGGNTSLAKKGETLADSVQVISSYVDAYVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTL
LDLFSIAETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFDNICFYFVAPEALAMPDYICEELDEAGIKY
QLLTDMEDVIPELDVLYMTRVQKERFDESEYAHIKSAYILTAALLENARDNLKVLHPLPRVDEITVDVDK
TPYAYYFQQAENGVYAREALLALVLNETL

Vibrio splendidus

>Vibrio splendidus LGP32]
MANSLYQKHIISIPELSREELELIVQTAGQLKAEPNPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGD
VIGFDSGGNTSLAKKGETLADSVQVISSYVDAYVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTL
LDLFSIAETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFDNICFYFVAPEALAMPDYICEELDEAGIKY
QLLTDMEDVIPELDVLYMTRVQKERFDESEYAHIKSAYILTASMLENARDNLKVLHPLPRVDEITVDVDK
TPYAYYFQQAENGVYAREALLALVLNETL

Vibrio vulnificus

>Vibrio vulnificus CMCP6]
MTNSLYKKHIISIPELSRAELELIVKTAGQLKAEPNPELIKNKVVASCFFEPSTRTRLSFETAIQRIGGD
VIGFDDGGNTSLAKKGETLSDSVQVISNYVDAFVMRHPQEGAARLASEFSNGVPVINAGDGANQHPTQTL
LDLFTISETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFNNIRFFFVAPDALAMPDYILEDLDEAGISY
SLHTDMETVIPELDILYMTRVQKERFDESEYAHIKSAYILTAALLEGARENLKVLHPLPRVDEITTDVDK
TPHAYYFQQAGNGVYAREALLALVLNESL

Non-salt loving organisms with top hits

Methanosaeta thermophila- thermophilic archaea

>Methanosaeta thermophila PT]
MLKRRHVLSMKDFSREEIDEILETAESLEPYARGKGSDILEGKILALMFFEPSTRTRMSFETAMKRLGGK
TINLGSAEASSIAKGESLADTIRVVGGYADAIVIRHPKEGSARLAAEFSPVPVLNAGDGAGHHPTQTLLD
LYTIKKESHLDDLSIALVGDLKYGRTVHSLAYALSLYGADIYLVSPPTLRMPEQIIGDLSRMGTRVREVS
DLREVIKEVDVLYITRIQRERFPDPVEYNRVARSYSITIRDLEGVKPELRIMHPLPRVDEISPSVDETEH
AVYFRQSFYGVPVRMALLKMILED

Archaeoglobus fulgidus- sulfur reducing archaea

>Archaeoglobus fulgidus DSM 4304]
MMRHLISIGDLDREDINYILKKAEEFEDVARGEKKLRILEGKILGNLFFEPSTRTRMSFETAMKRLGGDV
INMTAQEASSIAKGETLADTIRVVSGYCDAIVIRHPLEGAARFAAENSSVPVINAGDGAGQHPTQTLLDL
YTIKKECGRLDGITIALMGDLKYSRTIHSLIKALALFDMRIYLISPEALALPEDIIEDVSAEIRRARLEE
VISEIDVLYVTRIQKERFPDEEEYRKVSGSYRITAETLKSAKDSMIVMHPLPRVDEIHPSVDSTKHARYF
QQSFYGVPVRMAILSEVML

Methanocaldococcus fervens- autotrophic hyperthermophilic archaea

>Methanocaldococcus fervens AG86]
MRHLISMKDIGKEEILEILEEAKKMEELLNTKRPLKLLEGKILATVFYEPSTRTRLSFETAMKRLGGEVI
TMTDLKSSSVAKGESLIDTIRVISGYADIIVLRHPSEGAARLASEYSQVPIINAGDGSNQHPTQTLLDLY
TIMREIGKIDGIKITFVGDLKYGRTVHSLVYALSLFNDVEMYFISPKELKMPRDIIEDLKSKNIKFYEKE
SLDEIGDDIDVLYVTRIQKERFPDPNEYEKVKGSYKIKKEYVEGKKFIIMHPLPRVDEIDYEVDNLPQAK
YFKQSFYGIPVRMAILKKLIEDNE

Chromobacterium violaceum - bacterium

>Chromobacterium violaceum ATCC 12472]
MYRKHIISIPDFSREELELVVDTAARLKQSPRGDLLQDKLVASCFFEPSTRTRLSFETAVQRLGGNIIGF
ADGGNTSAKKGETLADSIKIISSYTDAVVMRHPKEGAARLASEFSAVPVINGGDGSNQHPTQTLLDLFSI
RETQGRLDGLTVAFAGDLKYGRTVHSLAQALSLFGARFYFVSPEVLAMPDYICEELDEKGISYTVADSLE
AVIPEVDVLYMTRVQRERFDEAEFRKIQGQYALRADMLKHARPGMKVLHPLPRVDEIAVDVDATPHAYYF
EQAKNGVYARQALLSLVLNETV

Vibrio cholerae- bacterium causes cholera

>Vibrio cholerae 12129(1)]
MLKPPLWGAFLWLLENIGKTIMANSLYQKHIISIAELSRAELELIVKTAGQLKAQPNPELIKHKVVASCF
FEPSTRTRLSFETAIQRIGGSVIGFDNGGNTSLAKKGETLADSVRVIASYVDAFVMRHPQEGAARLASEF
SNGTPVINAGDGSNQHPSQTLLDLYSIYETQGRLDNLDVAFVGDLKYGRTVHSLAQALAKFDNNRFYFVA
PEALAMPDYICEELDEAGVKYQVFSDMESVIPELDILYMTRVQKERFDESEYAHIKSAYILTAAHLSEAR
SNLKVLHPLPRVDEITTDVDKTPHAYYFEQVENGVYAREALLALVLNESL

Aeromonas hydrophila- bacterium mainly found in warm areas

>Aeromonas hydrophila subsp. hydrophila ATCC 7966]
MQTMTNPLYKKHVISISDLTRPDMELVVATAQRLKAEPDTRLLKDKLVASCFFEASTRTRLSFETAVQRL
GGNIIGFADGGNTSAKKGETLADSIKIIGSYTDAVVMRHPKEGAARLASEFSRVPVINGGDGSNQHPTQT
LLDLFSIHETQGKLDGLNVAFVGDLKYGRTVHSLAQALSLFNCRFFFISPEALAMPDYICEELEEKGIQF
SVHETMEEVMPELDILYMTRVQKERFDETEYKHMAAKFVLEVATLEGAKPTMKILHPLPRVDEIDVAVDK
TPHAYYFQQAENGVYARQALLALVLNETV

Picrophilus torridus- thermoacidiphil archaea

>Picrophilus torridus DSM 9790]
MLKNNSVISINDLSDEDLNLIFNTADSMAGNLKNGSQIKTMSGRIMATLFFEPSTRTRLSFESAMQRLGG
SVISMADSKSSSTAKGETLADTTRMVSSYSDIIVVRHPLEGAARLVQKFSSRPVINAGDGSGEHPTQTLV
DLYTIKKSFGDINNLEISIIGDLRYGRTVHSLLLALSRYNVRINLVSPDLLRLPGHVMSRLKNIKINEYN
DLNNVIESSDVFYVTRIQRERFTDKNDYNKVIGTYGITEKDTEKMKENAIIMHPLPRVDEISSSVDNTKN
AKYFIQAANGIPVRMALISLILGD

Tolumonas auensis

>Tolumonas auensis DSM 9187]
MANPLYKKNILSIADLSRTDLELVVQTASQLKQSPRHDLLQHKVIASCFFEASTRTRLSFETAVHRLGGS
VIGFADAGNTSLAKKGETLADSVRVITSYTDAFVIRHPQEGAARLSAEFSSVPVINAGDGSNQHPTQTLL
DLFSIYETQGTLDGLKLAFVGDLKYGRTVHSLAQALSLFGARFYFISPEALAMPDYICEELTEKGIEFSF
HDTIEEVMPELDILYMTRVQKERFEESEYRHIAAKFVLSADELKTAKPNMKILHPLPRVDEIHTDVDDTN
HAYYFQQAGNGVYARQALLALVLNEEV

Thermoplasma acidophilum- archaea

>Thermoplasma acidophilum DSM 1728]
MLKNRSVVSIEDVDIDDLNDLFDLSDSMLKTIEKGGSTDLLRNRIMATLFYEPSTRTRLSFESAMHRLGG
SVITVSDVKTSSVAKGETLADTIRMASSYSDIIVIRHPLEGAARLASKFANKPVINAGDGSGQHPTQTIL
DLYTIKRETGSIDGKTITMVGDLRYGRTIHSLIIALSRFDVRINLVSPQILKLPEYVLTKIGDRSRIMEY
DDLSKVIEDTDVLYVTRIQKERFSDQNEYQSVIGSYSVDRDLVSRMKKDAIIMHPLPRIDEIKPEVDELP
QARYFKQAYYGVPVRMALIYRILGD