January 19, 2016

Article Discussion

"Responses of Python Gastrointestinal Regulatory Peptides to Feeding" (2001)

• Hormone and peptide levels are elevated after feeding.
• Organ morphology begins changing even before food hits the organ.

"Adaptive Regulation of Digestive Performance in the Genus Python" (2007)

• The post-prandial growth of the Small Intestine is attributed to hypertrophy rather than hyperplasia.
• Intracellular stores of protein contribute to increased intestinal mass and nutrient up-take.
• Lipid droplets from the meal also increase intestinal mass.

Questions to Consider:

• Do new proteins replace the intracellular stores of protein when stored proteins travel to the cell surface?
• Are cell division and apoptosis up-regulated?

Remember: we are only working with RNA.

Classwork

• Use Unix to download FastQC data analysis results.

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References

• Secor, Stephen M., et al. “Responses of python gastrointestinal regulatory peptides to feeding.” PNAS. 98. 24 (2001): 13637-13642.

Secor et al. (2001)

• Ott, Brian D., and Secor, Stephen M. “Adaptive regulation of digestive performance in the genus Python.” The Journal of Experimental Biology. 210 (2007): 340-356.

Ott and Secor (2007)