Server at Davidson College
Finds the combination of proteases that results in the smallest fragment
for the amino acid that is being targeted.
This tool allows the user to enter an amino acid sequence and an amino acid to target.
The user is digesting the protein using proteases and trying to obtain the smallest
fragment of amino acids around their targeted amino acid as possible. There is a list
of proteases that the user can choose from to try, or they can choose to try every
protease in the list. It is possible that the best choice (resulting in the smallest
fragment) is to simply use one protease. It is also possible that the best possibility
is a pair. Sometimes switching the order of digestions of the pair of proteases will
result in different fragments.