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Amino Acid Hydropathy Scores
|
Amino
Acid Name
|
One
Letter Code
|
Hydropathy Score |
| Isoleucine | I | 4.5 |
| Valine | V | 4.2 |
| Leucine | L | 3.8 |
| Phenylalanine | F | 2.8 |
| Cysteine | C | 2.5 |
| Methionine | M | 1.9 |
| Alanine | A | 1.8 |
| Glycine | G | -0.4 |
| Threonine | T | -0.7 |
| Tryptophan | W | -0.9 |
| Serine | S | -0.8 |
| Tyrosine | Y | -1.3 |
| Proline | P | -1.6 |
| Histidine | H | -3.2 |
| Glutamic acid | E | -3.5 |
| Glutamine | Q | -3.5 |
| Aspartic acid | D | -3.5 |
| Asparagine | N | -3.5 |
| Lysine | K | -3.9 |
| Arginine | R | -4.5 |
These scores are based on the values given by the original Kyte-Doolittle paper. Other scoring systems have been determined and are used in other hydropathy plots. See, for example a web site about experimentally determined hydrophobicity scales.
REFERENCES
Kyte, J. and Doolittle, R. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157: 105-132.